Clinical Study-Parkinsons Disease Dementia Study

Parkinson’s Disease Dementia (PDD) study

 ClinicalTrials.gov is the official US government website for all FDA approved medical trials for Parkinson’s Disease, Stroke, Dementia, Multiple Sclerosis, Alzheimer’s Disease, Traumatic Brain Injury and all other medical conditions.  It is available for anyone to look up and retrieve contact information for the investigator site(s) or study sponsor to contact if interested in participating in research studies.
The following  clinical trial information is being provided for informational purposes only and The NeuroCommunity Foundation is not responsible for the products under investigation or the studies themselves in any way.
For those interested in participating in the evaluation of a new product that Altura Pharmaceuticals is developing that is hoped to lessen the impact of Parkinson’s Disease Dementia (PDD) by improving wakefulness, cognitive and motor function, below is the  contact information .
  • Telephone contact: 866-446-4135
  • Email (confidential): studysite@alturastudies.com

Autoimmunity and Parkinsons Disease

Researchers have found the first direct evidence that autoimmunity — in which the immune system attacks the body’s own tissues — plays a role in Parkinson’s disease, the neurodegenerative movement disorder. The findings raise the possibility that the death of neurons in Parkinson’s could be prevented by therapies that dampen the immune response.

The study, led by scientists at Columbia University Medical Center (CUMC) and the La Jolla Institute for Allergy and Immunology, was published today in Nature.

“The idea that a malfunctioning immune system contributes to Parkinson’s dates back almost 100 years,” said study co-leader David Sulzer, PhD, professor of neurobiology (in psychiatry, neurology and pharmacology) at CUMC. “But until now, no one has been able to connect the dots. Our findings show that two fragments of alpha-synuclein, a protein that accumulates in the brain cells of people with Parkinson’s, can activate the T cells involved in autoimmune attacks.

“It remains to be seen whether the immune response to alpha-synuclein is an initial cause of Parkinson’s, or if it contributes to neuronal death and worsening symptoms after the onset of the disease,” said study co-leader Alessandro Sette, Dr. Biol. Sci., professor in the Center for Infectious Disease at La Jolla Institute for Allergy and Immunology in La Jolla, Calif. “These findings, however, could provide a much-needed diagnostic test for Parkinson’s disease, and could help us to identify individuals at risk or in the early stages of the disease.”

[Read more…]

Join the online clinical study

Have you heard of the NEW  online study that empowers people with PD to partner  with researchers and accelerate the development of break-though treatments?

The MJ Fox foundation has a new program called FOX INSIGHT.

It’s open to anyone with or without PD.

To learn more about it, go to: https://foxinsight.michaeljfox.org

The NeuroCommunity Foundation is here for you:

For information about Parkinson’s disease and other movement disorders, support groups, wellness programs, education events, and local resources in northern Los Angeles County, Ventura County, Central Coast & Central Valley, contact us here or call 818-745-5051 to speak with Jan D. Somers, MSW, LCSW, BCD, Education Director, Parkinson & Movement Disorder Information Center, The NeuroCommunity Foundation.

The NeuroCommunity Foundation is a non-profit foundation. We provide support groups, educational conferences, resources, research updates/ clinical trials information and PD events in the SFV/Ventura/Central Coast/ Inland Empire.

 As we rely on donations to continue providing these services at no charge, if you would like to support our efforts, you can donate with ease and security at our website or mail us your gift. Please make sure and note our website as a bookmark in your computer. It is:  www.neurocommunity.org 

 The NeuroCommunity Foundation is exempt from Federal income tax under section 501(c)(3) of the Internal Revenue Code. Donors may deduct contributions to the foundation as provided in section 170 of the Internal Revenue Code.

 Mailing Address: 

The NeuroCommunity Foundation

 23705 Vanowen St. # 216

 West Hills, CA 91307

 

Parkinson’s disease and Dystonia

Dystonia and Parkinson’s Disease

Have you ever experienced a painful cramped foot or curled, clenched toes as part of life with Parkinson’s? These symptoms can often be a tell-tale sign of dystonia — sustained and often painful muscle twisting, spasms and cramps. Dystonia can be an early symptom of PD, or it can develop later, as a side effect of levodopa.

People with Parkinson’s commonly experience dystonia as a cramp in the foot that causes the toes to curl and stay clenched. In fact, in some people, a foot dystonia induced by walking or running may be one of the very first signs of the illness.

More commonly people who are being treated for PD complain of painful dystonia of the foot on the more severely affected side. This painful cramp usually goes away after the first dose of PD medications. Less commonly in treated patients, dystonia can affect other body parts and come and go throughout the day.

Dystonia can affect other parts of the body too. It causes forceful twisting movements that, for example, can draw a person’s arm behind their back, or pull the head to the side or toward the chest. These movements are different from the flowing, writhing movements of dyskinesia, which are not painful.

Although people with PD sometimes have dystonia, it also is its own movement disorder — people can have dystonia without having PD. Whether dystonia is part of PD or not, it is caused by changes in an area of the brain called the basal ganglia, and is often treated with the same medications.

Common Symptoms

Pain. The twisting and cramping of muscles in dystonia are among the most painful symptoms experienced by people with PD.

Parts of the body affected by dystonia:

Arms, hands, legs and feet: involuntary movements and spasms.

Neck: may twist uncomfortably, causing the head to be pulled down, or to one side. This is called cervical dystonia or spasmodic torticollis.

Eyes: muscles around the eyes may squeeze involuntarily, leading a person to blink too much or to have difficulty opening the eyes.

Vocal cords and swallowing muscles: a person’s voice may sound strangled, hoarse or breathy.

Face and jaw: the jaw may open or close forcefully or there may be grimacing of the face.

[Read more…]

Clinical Study in Woodland Hills on Depression

ARE YOU SUFFERING FROM DEPRESSION?  ? ARE YOU OVER THE AGE OF 60?

Study in Woodland Hills at the UCLA  Satellite office – Motion Picture TV Fund building.

The UCLA Late-Life Mood, Stress and Wellness Program in the Geriatric Psychiatry Division is conducting a 6-month research study involving 12 weekly 60 minute session of either a health and education wellness class or a Tai Chi class. Participants will undergo two functional magnetic resonance imaging (fMRI) scans. A complete psychiatric evaluation will be provided. Subjects will not be charged for participation and will be compensated. You must be at least 60 years old.

If you or anyone you know is interested in participating, call for an appointment to see if you qualify or for more information at: (310) 794-9523.

.In the San Fernando Valley, the study will be conducted at the Motion
Picture Television Fund in Woodland Hills for most of the study

NOTE:There is a baseline trip to UCLA required in order for the subject
to be consented by the Primary  Investigator and get an MRI/blood draw. Additionally, the  subject would have to come in to UCLA near the end of the
study for a final assessment.

The study will be conducted by Helen Lavretsky, M.D. Protocol ID:IRB#15-000184 UCLA IRB Approved

The NeuroCommunity Foundation is here for you:

For information about Parkinson’s disease and other movement disorders, support groups, wellness programs, education events, and local resources in northern Los Angeles County, Ventura County, Central Coast & Central Valley, contact us here or call 818-745-5051 to speak with Jan D. Somers, MSW, LCSW, BCD, Education Director, Parkinson & Movement Disorder Information Center, The NeuroCommunity Foundation.

The NeuroCommunity Foundation is a non-profit foundation. We provide support groups, educational conferences, resources, research updates/ clinical trials information and PD events in the SFV/Ventura/Central Coast/ Inland Empire.

As we rely on donations to continue providing these services at no charge, if you would like to support our efforts, you can donate with ease and security at our website or mail us your gift. Please make sure and note our website as a bookmark in your computer. It is:  www.neurocommunity.org 

The NeuroCommunity Foundation is exempt from Federal income tax under section 501(c)(3) of the Internal Revenue Code. Donors may deduct contributions to the foundation as provided in section 170 of the Internal Revenue Code.

Mailing Address: 

The NeuroCommunity Foundation                            

23705 Vanowen St. # 216                              

West Hills, CA 91307

Ask the Pharmacist about new medication for Dyskenesia

Ask the Pharmacist: New drug approved for Parkinson’s treatment

Dr. Richard Hoffman 

Q: I heard that a new drug was approved for Parkinson’s disease. What can you tell me about it?

A: The U.S. Food and Drug Administration (FDA) recently approved Gocovri (amantadine extended-release capsules) for the treatment of dyskinesia in patients with Parkinson’s disease (PD) receiving levodopa-based therapy, with or without other dopaminergic medications.

Dyskinesias are unpredictable, unwanted and uncontrollable writhing, dance-like movements of the arms, legs or head. They occur in over half of all PD patients who take levodopa for four to six years, and increases to more than 90 percent of those patients who take levodopa for a decade or longer. In clinical studies Gocovri, when given once daily at bedtime, significantly reduced the incidence of dyskinesias and increased functional time with symptoms improved in patients with PD.

The most common side effects observed in studies of Gocovri were hallucinations, dizziness, dry mouth, peripheral edema, constipation, falls and decreased blood pressure upon arising (orthostatic hypotension).

It should be noted that immediate-release amantadine is an anti-viral agent that has been available for many years to treat or prevent the flu. It has also been used “off-label” to treat patients with PD, where it is given 2-3 times daily; however, clinical comparisons between Gocovri and generic immediate-release amantadine have not been studied.

Gocovri is the first and only FDA-approved medication for the treatment of dyskinesia in PD patients. As such, there will likely be a large cost difference between Gocovri and generic amantadine immediate release.

Dr. Richard P. Hoffmann, Pharm D, is a retired pharmacist and medical writer with over 40 years of experience. He currently serves as consumer representative on the FDA’s Advisory Committee for Peripheral & Central Nervous System Drugs and is a patient representative for FDA Advisory Committees related to Parkinson’s disease. Dr. Hoffman is also a research advocate for the Parkinson’s Disease Foundation.

The NeuroCommunity Foundation is here for you:

For information about Parkinson’s disease and other movement disorders, support groups, wellness programs, education events, and local resources in northern Los Angeles County, Ventura County, Central Coast & Central Valley, contact us here or call 818-745-5051 to speak with Jan D. Somers, MSW, LCSW, BCD, Education Director, Parkinson & Movement Disorder Information Center, The NeuroCommunity Foundation.

The NeuroCommunity Foundation is a non-profit foundation. We provide support groups, educational conferences, resources, research updates/ clinical trials information and PD events in the SFV/Ventura/Central Coast/ Inland Empire.

As we rely on donations to continue providing these services at no charge, if you would like to support our efforts, you can donate with ease and security at our website or mail us your gift. Please make sure and note our website as a bookmark in your computer. It is:  www.neurocommunity.org 

The NeuroCommunity Foundation is exempt from Federal income tax under section 501(c)(3) of the Internal Revenue Code. Donors may deduct contributions to the foundation as provided in section 170 of the Internal Revenue Code.

Mailing Address: 

The NeuroCommunity Foundation                             

 23705 Vanowen St. # 216                               

West Hills, CA 91307

Current clinical trials in California

 PD RESEARCH/TRIALS/STUDIES

CLICK on the CITY for detailed information

California

For detailed information on the following clinical trials, Copy and paste:   www.centerwatch.com/clinical.com  into your server and you will be taken to CenterWatch website

CLINICAL TRIALS by LOCATION

Garden Grove California 92845

Collaborative Neuro Science Network
Open Label Parkinson’s clinical research study

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Glendale California 91206

PAREXEL
Patients are needed to participate in a Phase 1 clinical research study evaluating a potential new treatment for Parkinson’s disease.

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Fountain Valley California 92708

A clinical trial to evaluate treatments using Amantadine ER Tablets and Placebo Tablets for patients with Parkinson’s Disease or Levodopa Induced Dyskinesias (LID)

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Fountain Valley California 92708-5153

A Phase 2 clinical study for patients with Parkinson’s Disease

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Fountain Valley California 92708

Patients are needed to participate in a clinical research study of Amantadine HCl ER (ALLAY-LID II) and Placebo to evaluate Parkinson’s disease or Levodopa Induced Dyskinesia (LID)

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Fresno California 93710

A Phase 2 clinical study for patients with Parkinson’s disease

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Irvine California

A clinical trial to evaluate treatments using Amantadine ER Tablets and Placebo Tablets for patients with Parkinson’s Disease or Levodopa Induced Dyskinesias (LID)

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Irvine California

Patients are needed to participate in a clinical research study of Amantadine HCl ER (ALLAY-LID II) and Placebo to evaluate Parkinson’s disease or Levodopa Induced Dyskinesia (LID)

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La Jolla California 92037

A clinical study for patients with Parkinson’s Disease

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Los Angeles California 90048

A clinical trial seeking patients for a research study for the treatment of Parkinson’s Disease (EPI-589)

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Los Angeles California 91403

Patients are needed to participate in a clinical research study for the treatment of All Diagnosed Health Conditions

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Pasadena California

A clinical trial to evaluate treatments using Amantadine ER Tablets and Placebo Tablets for patients with Parkinson’s Disease or Levodopa Induced Dyskinesias (LID)

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Pasadena California

Patients are needed to participate in a clinical research study of Amantadine HCl ER (ALLAY-LID II) and

Placebo to evaluate Parkinson’s Disease or Levodopa Induced Dyskinesia (LID)

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Reseda California

A clinical trial to evaluate treatments using Amantadine ER Tablets and Placebo Tablets for patients with Parkinson’s Disease or Levodopa Induced Dyskinesias (LID)

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San Diego California 92037

A clinical research study of BIIB054 and Placebo for the treatment of Parkinson’s Disease

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San Francisco California 94115

A clinical trial seeking patients for a research study for the treatment of Parkinson’s Disease (EPI-589)

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San Francisco California 94115

Patients are needed to participate in a clinical research study evaluating Activa PC+S for the treatment of Parkinson’s Disease or Primary Dystonia

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San Francisco California 94121

Patients are needed to participate in a clinical research study of interventional MRI for implantation of DBS electrodes and DBS electrodes to evaluate Parkinson’s Disease or Dystonia

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Valencia California 91355

Patients are needed to participate in a clinical research study of Deep Brain Stimulation to evaluate Parkinson’s Disease

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Ventura California

A clinical trial to evaluate treatments using Amantadine ER Tablets and Placebo Tablets for patients with Parkinson’s Disease or Levodopa Induced Dyskinesias (LID)

————————————————-

Ventura California

Patients are needed to participate in a clinical research study of Amantadine HCl ER (ALLAY-LID II) and Placebo to evaluate Parkinson’s disease or Levodopa Induced Dyskinesia (LID)

 

 

 

 

 

 

 

 

Research done for PD at International Space Station

 

Key Parkinson’s Protein Gets Starring Research Role on International Space Station

Posted: JULY 21, 2017  in Parkinson’s Today , Social Clips

When a resupply mission lifts off in August bound for the International Space Station, it will be carrying an important cargo for researchers studying Parkinson’s disease: a protein considered  to be a key to potential future therapies.

The leucine-rich repeat kinase 2 (LRRK2) protein will be the focus of an experiment conducted on the Space Station. It is hoped that the microgravity conditions aboard the Space Station will allow growth of larger, more regular LRRK2 protein crystals, which would help scientists solve the protein’s structure — providing valuable information for the design of optimized therapies to fight Parkinson’s disease (PD).

[Read more…]

New Research information for PD

PD Research news. Click on the colored link to take you there directly. 

Parkinson’s News Today: Researchers Discover Why Deep Brain Stimulation Causes Weight Gain in Parkinson’s Patients

Parkinson’s News Today: “Is Parkinson’s Disease Triggered by a Protein in the Stomach?”

Parkinson’s News Today: “Computer Games Under Study as Non-Drug Therapy for Parkinson’s Disease

Parkinson’s News Today: “New Microsoft Watch Can Quiet Parkinson’s Tremors

Parkinson’s News Today: “Biomarkers for Predicting Cognitive Decline in Parkinson’s Disease May Improve Future Clinical Trials

Parkinson’s News Today: “APDA Partners with Smart Patients to Support Parkinson’s Online Community

The NeuroCommunity Foundation is here for you:

For information about Parkinson’s disease and other movement disorders, support groups, wellness programs, education events, and local resources in northern Los Angeles County, Ventura County, Central Coast & Central Valley, contact us here or call 818-745-5051 to speak with Jan D. Somers, Education Director, Parkinson & Movement Disorder Information Center, The NeuroCommunity Foundation.

The NeuroCommunity Foundation is a non-profit foundation. We provide support groups, educational conferences, resources, research updates/ clinical trials information and PD events in the SFV/Ventura/Central Coast/ Inland Empire.

As we rely on donations to continue providing these services at no charge, if you would like to support our efforts, you can donate with ease and security at our website or mail us your gift. Please make sure and note our website as a bookmark in your computer. It is:  www.neurocommunity.org 

The NeuroCommunity Foundation is exempt from Federal income tax under section 501(c)(3) of the Internal Revenue Code. Donors may deduct contributions to the foundation as provided in section 170 of the Internal Revenue Code.

 

 

 

 

 

 

 

 

 

 

 

PD clinical trials

Clinical Research Trials

Click on the COLORED LINKS and it will take you directly to the website so you may obtain all the information!

1) Genetic Testing  Go to www.michaeljfox.org/ppmi-genetics ( click on colored link to go directly to this website)

2) Dyskinesia research Participation Learn more about trials and studies in dyskinesia by visiting Fox Trial Finder. ( click on colored link)

3) Speeding up to Slow Parkinson’s Down: New Study Shows Exercise Delays PD Progression ( click on colored link)

 

 

 

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Did you know that you can support The NeuroCommunity Foundation through your everyday online purchases? Amazon.com has a charitable program called AmazonSmile. It is a simple and automatic way for you to support The NeuroCommunity Foundation every time you shop, at no cost to you.

When you shop at AmazonSmile, you’ll find the exact same low prices, vast selection and convenient shopping experience as Amazon.com, with the added bonus that the AmazonSmile Foundation will donate 0.5% of the purchase price to The NeuroCommunity Foundation!

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Dear The NeuroCommunity Foundation friends,supporters and participants.

If you happen to shop at Ralphs and would like to support The NeuroCommunity Foundation, we would be most appreciative!. If you do shop at Ralphs, we will receive 1 % of your purchase through their community
contribution program. The NeuroCommunity Foundation's Non-Profit Org. number ( NP0 # ) is 82287

All you need to do is enroll online at www.ralphs.com OR by calling Ralphs at
800-443-4438 after September 1, 2016.

If you happened to enroll prior to Sept 1st, Ralphs requires you to register again.

For your convenience, step-by-step website registration instructions are found below or can be found at www.ralphs.com, click on Community, click on Community Contributions, click on ‘Enroll Now’. If you don’t have computer access, please call us at 1-800-443-4438 for assistance.

Use you Ralph’s Rewards Card to Contribute Here’s How:

If you do not have a Ralph’s online account
1. Go to www.ralphs.com/account/create
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