PD clinical trials

Clinical Research Trials

Click on the COLORED LINKS and it will take you directly to the website so you may obtain all the information!

1) Genetic Testing  Go to www.michaeljfox.org/ppmi-genetics ( click on colored link to go directly to this website)

2) Dyskinesia research Participation Learn more about trials and studies in dyskinesia by visiting Fox Trial Finder. ( click on colored link)

3) Speeding up to Slow Parkinson’s Down: New Study Shows Exercise Delays PD Progression ( click on colored link)




A new PD Study could pave way for patient specific treatments

A new study is released: This study cites that their analysis produced networks that mapped out how alpha-synuclein is related to other Parkinson’s genes through well-defined molecular pathways. “We now have a system to look at how seemingly unrelated genes come together to cause Parkinson’s and how they are related to the protein that misfolds in this disease,” said Khurana. To confirm their work, the researchers generated neurons from Parkinson’s patients with different genetic forms of the disease. They showed that the molecular maps generated from their analyses allowed them to identify abnormalities shared among these distinct forms of Parkinson’s. Prior to this, there was no obvious molecular connection between the genes implicated in these varieties of PD. “We believe these methods could pave the way for developing patient-specific treatments in the future,” Khurana observed. [Read more…]

Research study in Diagnosing PD

Study Points Toward Diagnostic Test for Parkinson’s

– Jan 20 2017 published in the December 5 online edition of JAMA Neurology,

Using a new technology, researchers were able to detect trace amounts of toxic alpha-synuclein protein in the cerebrospinal fluid of people with Parkinson’s disease (PD), but not in people without PD. Furthermore, the amount of the protein increased with severity of PD. The results, suggest that the technique could be developed as a test to diagnose and monitor Parkinson’s disease.

Today, doctors diagnose PD based on a person’s symptoms, including tremor and stiffness. But many PD symptoms can be subtle, especially early on in the disease. Additionally, many PD symptoms can overlap with those of other disorders, making early diagnosis difficult. There is an urgent need for a simple test or biomarker that can definitively diagnose PD. Scientists have looked at the alpha-synuclein protein as a possible biomarker since it’s known to clump in the brain cells of people with PD.

[Read more…]

Diabetes Drug May Be Effective in Treating Parkinson’s

Image result for photo new research

Diabetes Drug May Be Effective in Treating Parkinson’s

Written by David Mills | Published on December 7, 2016                     Journal: Science Translational Medicine

Human trials are expected to begin next year on a drug researchers hope will be the first to slow the progression of Parkinson’s disease.

Can a drug that was originally designed to treat diabetes become the world’s first medication to slow the progress of Parkinson’s disease? Researchers are confident enough in the drug’s ability that they are organizing human clinical trials to begin next year.

“We hope this will be a watershed moment for millions of people living with Parkinson’s disease,” Dr. Patrik Brundin, director of Van Andel Institute’s Center for Neurodegenerative Science, chairman of The Cure Parkinson’s Trust’s Linked Clinical Trials committee, and the study’s senior author, said in a statement.

[Read more…]

Information about Inhaled Version of PD medication


 Levodopa pill can wear off, but a powdered version can come to the rescue, study finds.      

WEDNESDAY, Oct. 12, 2016 (HealthDay News) — An inhaled version of the Parkinson’s drug levodopa can help when patients experience symptoms between doses of the pill form of the medication, a new, small study finds.

Levodopa can control the tremors, rigidity and difficulty maintaining balance and coordination associated with Parkinson’s disease. However, within two years, as many as half of all patients have rapid and unexpected loss of motor control during “off” periods, when the drug wears off between doses, the researchers explained.

“Off periods are considered one of the greatest unmet medical needs in the treatment of Parkinson’s, and typically increase in frequency during the course of the disease,” said lead researcher Michael Lipp. He is vice president of pharmaceutical development and technical operations at Acorda Therapeutics, the drug’s maker and funder of the study.

[Read more…]

Current research for treatment of Parkinsons disease

NEW RESEARCH  for PD treatments

Make sure and read the new and potentially promising research that is currently taking place. 

 1. New Way of Administering Apomorphine for PD Movement “wearing off” Periods.

2. Inhaled Levodopa to Treat PD Movement “wearing off” Periods

3. Probiotics and Fiber Formula to Reduce Constipation in Parkinson’s

[Read more…]

UCLA research study seeking PD participants

UCLA  is seeking participants for PD study

 “Perceptual Decision Making under Conditions Of Visual Uncertainty”

To volunteer or for more information:

Please write to APerugini@mednet.ucla.edu or call 310-825-0278

A UCLA research study,

“Perceptual Decision Making under Conditions
Of Visual Uncertainty”in the Basso laboratory at the Semel Institute for Neuroscience and HumanBehavior, INVITES YOU to be in a research study. The purpose of the research is to explain how brain regions that are affected by movement disorders are involved in eye movements and decision making.

[Read more…]

FDA Approves Nuplazid For Treatment Of PD Psychosis


On April 29th the U.S. Food and Drug Administration (FDA) approved Nuplazid (pimavanserin) tablets, the first drug officially authorized to treat hallucinations and delusions associated with psychosis experienced by some people with Parkinson’s disease.

Hallucinations or delusions can occur in as many as 50 percent of patients with Parkinson’s disease at some time during the course of their illness. People who experience them see or hear things that are not there (hallucinations) and/or have false beliefs (delusions). [Read more…]

Significant Findings About The Dopamine Transport System In The Brain

Thanks to Michael W. for sharing an article from ScienceDaily® with significant findings about the dopamine transport system in the brain. Researchers at the University of Florida Health have discovered the mechanics of how dopamine transports into and out of brain cells, a finding that could someday lead to more effective treatment [Read more…]

Smart Socks Gait Monitoring System Research Study

smart socks

Participants needed for a new research study at Casa Colina Hospital and Centers for Healthcare in Pomona to evaluate Smart Socks Gait Monitoring System for improving rehabilitation outcomes. The Sensoria Smart Socks gait monitoring system is a pair of socks and anklet bands that provide real-time monitoring of gait. Falls and subsequent health issues related to challenges in gait (walking) can occur when individuals are recovering from a stroke or brain injury or are dealing with progressive neurological disorders such as Parkinson’s Disease (PD) or Multiple Sclerosis (MS). The goal of the research study is [Read more…]

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